Our research focuses on

Mechanisms of cellular dysfunction and cognitive decline in aging brain

To explore mechanisms underlying cellular dysfunction and cognitive decline in the aging brain.   Decades of research have gone into cataloguing the changes that occur in every cellular system with age Declines in the protein quality control mechanisms, mitochondrial function,

Genetic risk factors for neurodegeneration

Studying the effect of genetic risk factors for neurodegenerative diseases using human iPSCs.   Recent genome-wide association studies (GWAS) have revealed a number of novel genetic risk factors associated with neurodegenerative diseases including Alzheimer’s disease (AD). Now, it is time

The effect of environmental factors and lifestyle on Alzheimer’s disease

To explore how environmental factors and lifestyle contribute to the onset and progress of Alzheimer’s disease.   Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by profound memory loss, disruptions in thinking and reasoning, and changes in personality and